利用氟—18—FDG正子掃描偵測絨毛膜癌病人之肺部轉移

Detection of lung metastasis in a choriocarcinoma patient by FDG-pet scan

張祐銓(Yu-Chen Chang) ； 閻紫宸(Tzu-Chen Yen) ； 曾凱元(Kai-Yuan Tzen)

《核子醫學雜誌》 15卷2期 (2002/06) Pp. 103-105

https://doi.org/10.6332/ANMS.1502.009

摘要

一位37歲女性患者在子宮外孕手術後2個月，出現大量月經及陰道出血情形。血液β-hCG值高達78138mIU/mL。經由子宮括除術，病理結果為妊娠滋養層疾病，高度懷疑絨毛膜癌。胸部Ｘ光發現右上肺有疑似小腫塊，但無法確定其良惡性。其後接受子宮切除及多次化學治療，血液β-hCG仍繼續上升。氟-18-FDG正子掃描右上肺外側有一葡萄糖代謝較高區域。外科進行切除肺部病灶。病理結果證實為轉移性絨毛膜癌。本文顯示氟-18-FDG正子掃描可以成功地偵測絨毛膜癌轉移灶。

關鍵字

絨毛膜癌 ； 肺部轉移 ； FDG ； PET

並列摘要

This is a 37-year-old female who had laparotomy for ectopic pregnancy. Two months later, she had large amount of mense and vaginal spotting. The level of blood ß-hCG was 78138 mIU/mL. Curettage was then performed and pathological report showed gestational trophoblastic disease, with choriocarcinoma highly suspected. Chest X-ray showed a suspected small round nodule in right upper lung, but the nature of this lesion was yet to be determined.She had hysterectomy and received several courses of chemotherapy later. However, the titer of ß-hCG was still elevated. 18F-FDG-PET scan showed a hypermetabolic lesion in the right upper lateral lung field. After surgical resection
of this lesion, the pathology showed metastatic choriocarcinoma. In this case, we demonstrated that 18F-FDGPET
scan can successfully detect metastatic lesion in a choriocarcinoma patient.

並列關鍵字

choriocarcinoma, lung metastasis, FDG, PET