稀釋顯影劑技術在PET-CT影像之應用

The Application of Dilute Contrast Media in PET-CT Imaging

李基訓(Chi-Hsun Li) ； 王素貞(Su-Chen Wang) ； 陳錦薰(Jiin-Shiun Chen) ； 陳明宗(Ming-Tsung Chen) ； 陳遠光(Yen-Kung Chen) ； 沈業有(Yeh-You Shen) ； 蘇誠道(Cheng-Tau Su)

《核子醫學雜誌》 16卷1期 (2003/03) Pp. 25-29

https://doi.org/10.6332/ANMS.1601.005

摘要

Background:2 [18F]fluoro-2-deoxyglucose(FDG)positron emission tomography(PET)has been a rapidly progressive and modern nuclear medicine diagnostic technology for oncology in the past few years. By fusion of PET images with computed tomography(CT)images, PET-CT can integrate anatomic information with abnormal tracer uptake lesions into one set of image data to improve diagnosis significantly. Since the attenuation correction of PET-CT is achieved by CT, it is difficult to differentiate the organs if they have similar attenuation coefficients. In this study, we evaluated usefulness of intake of contrast media in patients with abnormal FDG uptake in the abdomen and the pelvis. Method: Twenty-three patients with gynecological or gastrointestinal diseases(12 male patients,11 female patients; mean age:52 years)underwent FDG-PET-CT imaging before and after oral ingestion or enema of dilute contrast media. The images were read and scored(full score was 10)by 3 experienced nuclear medicine physicians and were analyzed with paired t-test. Results: The mean scores for pre-contrast images and post-contrast images were 6.25±1.07 and 9.12±0.57,respectively.Paired t-test analysis revealed the significant difference(P＜0.01)between pre-contrast images and post-contrast images. Conclusion: We conclude that using dilute contrast media can enhance the quality of PET-CT images and improve the diagnosis capability of physicians for the diseases in abdomen region.

關鍵字

正子電腦斷層攝影 ； 電腦斷層攝影 ； 含碘顯影劑 ； 影像融合

並列摘要

Background:2 [18F]fluoro-2-deoxyglucose(FDG)positron emission tomography(PET)has been a rapidly progressive and modern nuclear medicine diagnostic technology for oncology in the past few years. By fusion of PET images with computed tomography(CT)images, PET-CT can integrate anatomic information with abnormal tracer uptake lesions into one set of image data to improve diagnosis significantly. Since the attenuation correction of PET-CT is achieved by CT, it is difficult to differentiate the organs if they have similar attenuation coefficients. In this study, we evaluated usefulness of intake of contrast media in patients with abnormal FDG uptake in the abdomen and the pelvis. Method: Twenty-three patients with gynecological or gastrointestinal diseases(12 male patients,11 female patients; mean age:52 years)underwent FDG-PET-CT imaging before and after oral ingestion or enema of dilute contrast media. The images were read and scored(full score was 10)by 3 experienced nuclear medicine physicians and were analyzed with paired t-test. Results: The mean scores for pre-contrast images and post-contrast images were 6.25±1.07 and 9.12±0.57,respectively.Paired t-test analysis revealed the significant difference(P＜0.01)between pre-contrast images and post-contrast images. Conclusion: We conclude that using dilute contrast media can enhance the quality of PET-CT images and improve the diagnosis capability of physicians for the diseases in abdomen region.

並列關鍵字

positron emission tomography ； computed tomography ； contrast media ； image fusion