- 期刊
Left Ventricular Ejection Fraction Measured from (superscript 99m)Tc-Sestamibi Myocardial Perfusion Gated SPECT: Comparison with Echocardiography
使用鎝－99m-sestamibi心肌灌注門控單光子斷層掃描測量左心室搏出分率：與心臟超音波做比較
摘要
目的：本研究目的在比較鎝－99m-sestamibi心肌灌注門控單光子斷層掃描與心臟超音波(M-mode)所計算之左心室搏出分率。 方法：本回溯性研究總共收集了43位病人（19位男性，24位女性，年齡從31歲到85歲，平均65.3±11.7歲），他們在一個月內接受心肌灌注門控單光子斷層掃描和心臟超音波兩種檢查，心肌灌注門控單光子斷層婦描採用鎝－99m-sestamibi休息相／藥物模擬壓力相流程，我們採用一種手動方式（改良Simpson公式）和兩種自動化電腦軟體（Auto QUANT-QGs和4D-MSPECT）分別測量壓力相心肌灌注門控單光子斷層掃描的左心室縛出分率，ZD引導M-mode心臟超音波則是採用Teichholz公式計算左心室縛出分率。 結果：心肌灌注門控單光子斷層掃描所計算之左心室搏出分率平均值如下：手動方式爲63.6±10.6%、Auto QUANT-QGS爲64.7±14.3%、4D-MSPECT爲65.1±12.6%，左心室搏出分率在這三種分析方式中並沒有顯著的差異（P值均大於0.05），而且都具有好的相關性（P值均小於0.0l）。M-mode心臟超音波所計算之左心室搏出分率平均值爲67.8±12.5%，與心肌灌注門控單光子斷層掃描的手動方式•Auto QUANT-QGs和4D-MSPECT之相關係數分別爲0.84、0.77和0.74（P值均小於0.01），然而M-mode心臟超音波所計算之左心室搏出分率數值大於手動方式與Auto QUANT-QGs有顯著意義（P值分別爲小於＜0.01和0.03）。 結論：鎝－99m-sestamibi心肌灌注門控單光子斷層掃描與心臟超音波所計算之左心室搏出分率具有良好的相關性。
並列摘要
Purpose: The aim of this study was to compare the estimated LVEF between 99mTc-sestamibi myocardial perfusion gated SPECT and M-mode echocardiography. Methods: A total of 43 patients (19 males, 24 females, mean age of 65.3±11.7 years, range from 31 to 85 years) undergoing myocardial perfusion gated SPECT with a one-day 99mTc-sestamibi rest/dipyridamole stress protocol and echocardiography within one month were enrolled into this retrospective study. The measurements of LVEF from stress myocardial perfusion gated SPECT were performed with a manual method (modified Simpson's formula) and two automatic software packages (Auto QUANT-QGS and 4D-MSPECT). The LVEF was also estimated with 2D-guided M-mode echocardiography (Teichholz formula). Results: In myocardial perfusion gated SPECT, the means±SD of LVEF estimated with manual method, Auto QUANT-QGS, and 4D-MSPECT were 63.6±10.6%, 64.7±14.3%, and 65.1±12.6% respectively. The values of LVEF had no significant differences between each other of the three methods (all P ＞0.05). The values of LVEF also correlated well between each other of the three methods (all P＜0.01). The mean±SD of LVEF estimated with echocardiography was 67.8±12.5%. In comparison with echocardiography, the correlation coefficients of the manual method, Auto QUANT-QGS, and 4D-MSPECT were 0.84, 0.77, and 0.74 respectively (all P ＜0.01). However, the values of LVEF from echocardiography were significantly higher than the manual method and Auto QUANT-QGS (P＜0.01 and 0.03, respectively). Conclusion: The values of LVEF estimated from 99mTcsestamibi myocardial perfusion gated SPECT correlated well with M-mode echocardiography.
延伸閱讀
- Huang, W. C., Chiou, K. R., Liu, C. P., Lee, D., Mar, G. Y., Hsiao, S. H., Chiou, C. W., Kung, M. H., & Lin, S. L. (2004). 早期評估急性心肌梗塞病患無法收縮及收縮困難的左心室心肌之存活性：比較即時造影劑超音波和低劑量dobutamine 心臟超音波. Acta Cardiologica Sinica, 20(3), 160-170. https://www.airitilibrary.com/Article/Detail?DocID=10116842-200409-20-3-160-170-a
- Wang, Y. F., Lin, T. K., Chen, C. W., Chiu, J. S., & Lin, C. L. (2006). 鉈－201心肌灌注造影之逆再分佈現象：以同步閘門單光子心室壁運動造影提升診斷之準確性. 慈濟醫學雜誌, 18(2), 101-108. https://doi.org/10.6440/TZUCMJ.200604.0101
- Hung, G. U., Hsia, C. H., Yang, P. T., & Yang, K. T. (2005). 鉈-201心電圖同步心肌灌注電腦斷層掃描在評估左心室功能的效用. The Kaohsiung Journal of Medical Sciences, 21(5), 203-211. https://www.airitilibrary.com/Article/Detail?DocID=02575655-200505-21-5-203-211-a
- 鄭時維、徐健欽、方淑屏、邱志宏（2009）。應用雙同位素休息相鉈－201與壓力相鎝－99m sestamibi心肌灌注造影診斷冠狀動脈疾病。台灣應用輻射與同位素雜誌，5(3)，721-727。https://doi.org/10.29832/TJARI.200909.0004
- 張驊嫣（2015）。利用多切面電腦斷層冠狀動脈影像評估合理左心室分率估算之方法〔碩士論文，義守大學〕。華藝線上圖書館。https://doi.org/10.6343/ISU.2015.00160