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Bone Scan-Like Appearance on the FDG PET/CT Image: A Patient with Primary Bone Marrow Diffuse Large B-Cell Lymphoma

類似骨骼掃描表現之氟化去氧葡萄糖正子電腦斷層影像:一骨髓原發瀰漫型大B細胞淋巴瘤之病例

摘要


一位68歲婦女出現發燒及全血細胞減少症狀。包括鎵全身掃描等傳統影像檢查無法查出可能的發炎或腫瘤病灶。病患接受進一步評估之骨髓穿刺切片檢查,病理結果呈現瀰漫型大B細胞淋巴瘤,懷疑是骨髓原發型。後續的氟化去氧葡萄糖正子電腦斷層造影呈現氟化去氧葡萄糖於全身骨髓極明顯且廣泛的攝取,以及脾臟有增強的氟化去氧葡萄糖累積。這個類似骨骼掃描表現之氟化去氧葡萄糖正子電腦斷層影像,臨床上幫助確定了骨髓原發淋巴瘤合併脾臟侵犯(即骨髓、肝臟和/或脾臟型)之診斷。

並列摘要


A 68-year-old woman presented with fever and pancytopenia. Conventional imaging surveys including gallium scan failed to identify the possible inflammatory or neoplastic foci. Bone marrow biopsy was performed for further survey and the pathological result showed diffuse large B-cell lymphoma with suspicion of primary bone marrow type. A following FDG PET/CT scan revealed a striking disseminated FDG uptake in whole-body bone marrow and the increased FDG accumulation in the spleen. The "bone scan-like" appearance on the FDG PET/CT scan helped to confirm the diagnosis as primary bone marrow lymphoma with probable spleen involvement, the bone marrow, liver and/or spleen (BLS) type.

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