Primary adenocarcinoma of the appendix is rarely encountered and is usually discovered incidentally on pathological examination of surgical specimens. Appendiceal cancer has no distinct pathognomonic symptoms and there are no useful preoperative diagnostic tools available to detect it. We report a case of a 36-year-old man with appendiceal adenocarcinoma with suppurative appendicitis who presented with signs and symptoms of acute appendicitis. Appendectomy was performed through a McBurney's incision. When the pathology report confirmed appendiceal adenocarcinoma, however, further treatment and further surgery were refused. The aim of this report is to review the relevant literature and to increase awareness of appendiceal neoplasms.