Septic Thrombophlebitis of the Internal Jugular Vein (Lemierre's Syndrome): A Case Report

Lemierre氏症候群是一種急性口咽炎感染合併敗血性內頸靜脈血栓靜脈炎，罕見且具高致病率與致死性，多與Fusobacterium necrophorum感染相關，常見多發轉移性膿瘍。我們報告一四十二歲男性，起初以急性喉痛及發燒表現，其頸部電腦斷層發現右側扁桃腺炎合併內頸靜脈血栓，另外胸部影像發現局部肺浸潤。經過抗生素與抗凝血劑投與一週之後，此病人已被成功治療後出院。此疾病常見於年輕人且初期臨床表現酷似急性上呼吸道感染，容易被醫療人員疏忽而延遲治療，在此提出一病例報告以提醒急診醫師早期給予適當治療。

關鍵字

內頸靜脈； Lemierre氏症候群；敗血性血栓靜脈炎

並列摘要

Lemierre's syndrome, also known as postanginal septicemia, is a rare but serious clinical entity with significant mortality and morbidity. The disease is usually caused by an anaerobic infection of the oropharynx, frequently with septic thrombophlebitis of the internal jugular vein complicated with multiple metastatic infections. Herein, we present a 42-year-old man of Lemierre's syndrome diagnosed via enhanced computed tomography of the neck and blood culture (Fusobacterium necrophorum). He suffered from acute onset of sorethroat, dysphagia and fever with chills for several days. Septic pulmonary embolism was documented by the chest radiograph. Intravenous empiric antibiotics with augmentin(superscript ®) and anticoagulation therapy with enoxaparin plus warfarin were administered. The patient was uneventful one week later and discharged without complications. Lemierre's syndrome is a rare and life-threatening disease, which usually affects young adults and typically presents as metastatic infection of the lung. Delayed recognition may lead to significant morbidity of metastatic infections and sepsis. Early and adequate administration of intravenous antibiotic therapy is generally associated with a good outcome.

並列關鍵字

internal jugular vein ； Lemierre's syndrome ； septic thrombophlebitis

國際替代計量

Septic Thrombophlebitis of the Internal Jugular Vein (Lemierre's Syndrome): A Case Report

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