高壓氧治療對糖尿病患者血糖數值之影響

The Effect of Hyperbaric Oxygenation on Blood Sugar Level in DM Patients

黃吉田(Chi-Tien Huang) ； 黃耀興(Yao-Hsing Huang) ； 張陸澎(Lu-Peng Chang)

《中華職業醫學雜誌》 11卷4期 (2004/10) Pp. 235-242

https://doi.org/10.30027/CJOM.200410.0004

摘要

高壓氧治療應用於困難傷口之糖尿病足是非常普遍的。文獻發現糖尿病足患者在接受高壓氧治療期間，有些會有血糖值降低，甚至會出現低血糖情形，因而引發我們探討高壓氧治療對於糖尿病患者血糖值的影響。本次實驗以接受高壓氧治療之糖尿病足部潰痬病患25人爲實驗組（於門診或住院接高壓氧治療之病患），對照組24人（未接受高壓氧治療之糖尿病足部潰痬住院病患）。統計兩組之間的血糖變化差異值，結果實驗組下降斜率爲-2.53對照組爲-4.09，文中有討論爲何下降斜率較小的可能原因。另外在細分高壓氧治療的次數超過（含）20次爲A組，血糖值平均減少爲48mg/dl(22.4%)，高壓氧治療的次數小於20次爲B組，其平均血糖值下降14.9mg/dl(8.03%)，由此結果得知，實驗組中高壓氧治療的次數愈多，血糖控制的愈理想。K.Parker定義當血糖低於100mg/dl視爲低血糖，本次實驗發生低血糖比率約爲9.7%，所以高壓氧治療期間最應避免的是糖尿病低血糖的併發症。

關鍵字

糖尿病 ； 糖尿病足 ； 高壓氧治療 ； 血糖值

並列摘要

Hyperbaric Oxygen Treatment (HBOT) is commonly used to treat non-healing wound in diabetic patients. From anecdotal evidences, we have learned HBOT may contribute to drop blood sugar level, even hypoglycemic episode. Therefore it is the motivation for us to initiate this study.
We collect two groups of patients with DM foot ulceration, in which one is receiving HBOT(experimental group) and the other one is Non-HBOT group(control group), who are admitted to our hospital. Afterwards we compared with their variations of blood sugar pattern, and found the decreasing slope of HBOT is-2.53 and Non-HBOT is-4.09.from this researchable material we investigated the possible mechanisms in this article.
Besides, we divided the HBOT patients (experimental group) into group A (HBOT＞20 sessions) and group B (HBOT＜20 sessions). The average blood sugar level decreases by 48mg/dl (22.4%) in group A and 14.9mg/dl (8.03%) in group B. It seemed that the more sessions of HBOT is the better blood sugar control.
K.Paker defined “low blood sugar”(LBS) as any blood glucose below l00mg/dl. According to our study the LBS incidance is 9.7%. So the hypoglycemic complication should be highly avoided during HBOT in diabetic patients.

並列關鍵字

Diabetes mellitus ； DM foot ； Hyperbaric oxygen treatment ； Blood sugar level