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Salmonella Lung Abscess and Empyema in a Patient with Metastatic Papillary Thyroid Carcinoma: A Case Report

轉移性乳頭狀的甲狀腺癌症病患併發沙門桿菌肺膿瘍及膿胸:病例報告

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摘要


沙門桿菌屬所引起的肺部感染是非常少見的。而其中以鼠傷寒桿菌(S. typhimurium)和豬霍亂桿菌(S.choleraesuis)所引起的肺部感染是較為常見的。它們通常發生在那些具有潛在嚴重的系統性疾病、肺部或肋膜有結構性的異常、或者是免疫系統受到抑制的人身上。由nontyphoid Salmonella 所引起的肋膜肺部感染的確實發生率目前並不清楚。但據我們的了解,由nontyohoid Salmonella (Salmonella enteritidis腸炎桿菌)在癌症病人身上,所造成的肺氣腫和肺膿瘍,目前還沒有被報導過。我們在這裹報告一個病例,這是一位七十一歲的女性病人,她原本就有轉移性乳頭狀的甲狀腺癌症,被發現有肺氣腫和肺膿瘍產生。從肺氣腫和肺膿瘍所形成的痰和膿液培養出Salmonella enteritidis。一開始先用ceftazidime治療,後來再改用 cefatriazone治療,但是最後病人還是因為併發無法控制的二度感染、敗血症和多發性器官衰竭而死亡

並列摘要


Pulmonary infections caused by Salmonella species are very uncommon. Among them, S. typhimurium and S. choleraesuis are the salmonella species most commonly responsible for respiratory infection. They usually occur in people with severe underlying diseases, preexisting abnormalities of the lung or pleura, or in patients with a suppressed immune system. The true incidence of pleuropulmonary infections due to nontyphoid Salmonella is not known. To our knowledge, empyema and lung abscess induced by nontyphoid salmonella (Salmonella enteritidis) in a patient with malignant disease has not been reported yet. We present a case of a 71-year-old female with empyema and lung abscess with underlying metastatic papillary thyroid carcinoma. Salmonella enteritidis was isolated from the lung abscess, empyema fluid, and sputum. She was first treated with antibiotics ceftazidime and then changed to cefatriazone, but she expired later due to uncontrolled secondary infection, septicemia, and multiorgan failure.

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