Recurrent Juvenile-Onset Laryngotracheal Papillomatosis with Pulmonary Parenchymal Spread: A Case Report

復發性幼年型喉與氣管的乳頭狀瘤病併肺擴散：病例報告

李建德(Jiann-Der Lee) ； 張基晟(Gee-Chen Chang) ； 黃枝梅(Chih-Mei Huang) ； 沈光漢(Gwan-Han Shen) ； 江自得(Chi-Der Chiang)

《胸腔醫學》 15卷3期 (2000/09) Pp. 152-156

摘要

一位30歲女性病人於七歲時被診斷為幼年型喉與氣管的乳頭狀瘤病，初期症狀為聲音沙啞與上呼吸道阻塞，隨後接受二氧化碳雷射切除及氣切手術。復發後再多次接受二氧化碳雷射切除術及局部acyclovir藥膏塗抹，但效果並不令人滿意。最近因呼吸困難與發燒症狀求診，意外發現X光檢查肺部有多處空洞病灶，支氣管鏡檢証實有支氣管內乳頭狀瘤病擴散。回顧過去的文獻，呼吸道乳頭狀瘤病擴散至氣管，支氣管及肺部是相當罕見。

並列摘要

A 33-year-old female patient with juvenile-onset laryngotracheal papillomatosis had presented with hoarseness and upper airway obstruction at 7 years old, and received a CO2 laser papillectomy and tracheostomy. Papillomatosis recurred and underwent repeated CO2 laser and local acyclovir cream treatments, but with no appreciable improvement. During the last month, progressive shortness of breath, dyspnea on exertion, and fever had developed. Multiple cavitary lesions were found incidentally on chest radiography. A bronchoscopy was performed and papillomatosis was confirmed, with bronchial and lung spread. A review of the literature has shown that respiratory tract papillomas distally extending into the trachea, bronchi, and lung parenchymal are rarely seen.

並列關鍵字

laryngotracheal papillomatosis