Pulmonary Metastatic Malignant Melanoma with Endobronchial Involvement: A Case Report and Literature Review

肺部轉移性惡性黑色素細胞瘤合併支氣管內侵犯－一病例報告與文獻回顧

劉偉倫(Wei-Lun Liu) ； 古世基(Shih-Chi Ku) ； 楊泮池(Pan-Chyr Yang)

《胸腔醫學》 21卷2期 (2006/04) Pp. 182-189

https://doi.org/10.29806/TM.200604.0007

摘要

罹患肺外惡性腫瘤而造成死亡的病人，約有2~5%在屍體解剖時會發現有支氣管內轉移。惡性黑色素細胞瘤在生長的過程中常有轉移至肺部的現象，但是支氣管內轉移則是非常罕見。我們報告一個肺部轉移性惡性黑色素細胞瘤合併支氣管內侵犯的病例，病人以咳嗽及咳血為主要表現，並經由支氣管鏡檢查及支氣管切片確立診斷。藉由這位病人其腫瘤在支氣管鏡下的特殊表現，彰顯了支氣管鏡對於支氣管內腫瘤的鑑別診斷之重要性。此外，我們並就肺部轉移性惡性黑色素細胞瘤合併支氣管侵犯之臨床表徵，影像學表現，診斷方式，以及治療的方向等方面，回顧相關的文獻報告。

關鍵字

支氣管內轉移 ； 肺部轉移性惡性黑色素細胞瘤 ； 支氣管鏡

並列摘要

Endobronchial metastasis is found in 2-5% of patients at autopsy who die from extrathoracic cancer. Malignant melanoma has a tendency to metastasize to the lung during the course of tumor growth, but endobronchial metastasis is rare. We report a case of pulmonary metastatic malignant melanoma with endobronchial involvement presenting with cough and hemoptysis, which was diagnosed by fiberoptic bronchoscopy with bronchial biopsy. The specific bronchoscopic picture highlights the value of bronchoscopy in the differential diagnosis of endobronchial tumor. The relevant literature is reviewed, including clinical manifestations, image presentations, diagnosis, and treatment options.

並列關鍵字

endobronchial metastasis ； malignant melanoma ； fiberoptic bronchoscopy