Pulmonary Benign Metastasizing Leiomyoma: A Case Presentation and Review of the Literature

肺部良性轉移性平滑肌瘤－病例報告與文獻回顧

姜佑承(You-Cheng Jiang) ； 林旻希(Min-Hsi Lin) ； 賴瑞生(Ruay-Sheng Lai)

《胸腔醫學》 32卷6期 (2017/12) Pp. 259-265

摘要

Uterine leiomyoma is a common benign tumor in women of reproductive age. In rare cases, distant metastasis can develop months to years after gynecological procedures. Metastasis to the lung, or pulmonary benign metastasizing leiomyoma (PBML), is the most common type. Patients are usually asymptomatic and the tumor is found incidentally on routine chest x-ray. The typical radiological presentation is multiple pulmonary nodules. Management includes observation, surgery, or hormonal manipulation. There is increasing evidence of partial regression of PBML with the use of hormone therapy. We report the case of a 46-year-old woman who presented with diffuse lung cysts complicated by pneumothorax. In this case, a decreasing cyst size and number were observed after only 3 months of hormone therapy.

關鍵字

pulmonary benign metastasizing leiomyoma ； pneumothorax ； hormone therapy

並列摘要

子宮肌瘤是生育年齡女性最常見的良性腫瘤，然而接受子宮肌瘤切除手術的病患在數月或數年後卻可能罕見地出現遠端轉移；轉移至肺部最常見，此時稱為肺部良性轉移性平滑肌瘤。大部分病患都無症狀，直到意外在影像上發現肺結節才被診斷。治療的選項有追蹤、手術切除、以及荷爾蒙治療，荷爾蒙治療有越來越多成功的案例。我們報告一位46歲的女性病人，罕見的以肺囊腫併發氣胸來表現。本病患接受3個月荷爾蒙治療後，肺囊腫隨即變小與數量變少。

並列關鍵字

肺部良性轉移性平滑肌瘤 ； 氣胸 ； 荷爾蒙治療