Penicillium marneffei Lung Abscess and Fungemia in a Patient with Acquired Immunodeficiency Syndrome

馬菲氏青霉菌肺膿瘍及黴菌血症在後天免疫不全症候群之病例報告

詹雲翔(Yun-Hsiang Chan) ； 楊靖慧(Chin-Hui Yang) ； 陳寬榮(Kuan-Jung Chen)

《胸腔醫學》 20卷5期 (2005/10) Pp. 471-477

https://doi.org/10.29806/TM.200510.0016

摘要

馬菲氏青霉菌(Penicillium marneffei)是東南亞區域的地方性黴菌，其可對免疫力正常或不正常的人造成感染，早期的診斷和適當的用藥通常可以治癒，但延遲診斷則常常造成病人的死亡。我們在此報告一個在東南亞有過性交易的後天免疫不全症候群的病人，在疾病早期即以發燒和肺部空洞為表現而被診斷為肺部結核病治療，在經黴菌培養確定病原為馬菲氏青霉菌後經適當治療而康復。並回顧歷年來對此種病歷相關的文獻報告。

關鍵字

馬菲氏青霉菌 ； 肺空洞 ； 後天免疫不全症候群

並列摘要

Penicililum marneffei is an opportunistic pathogen in patients with immunodeficiency syndrome or in immunocompetent persons living in endemic areas, including Southeast Asia. Successful treatment of the disease requires early diagnosis and proper antifungal therapy. Delayed diagnosis usually leads to death. We present the case of a patient with acquired immunodeficiency syndrome (AIDS), who had had a sexual experience in Southeast Asia, and who presented with fever and a lung cavitary lesion that was found on the chest film. Penicillium marneffei was isolated from fungal cultures of the blood and a lung aspirate. The patient recovered smoothly after antifungal therapy. We also review the associated literature.

並列關鍵字

Penicillium marneffei ； lung cavity ； AIDS