Infections caused by Cryptococcus neoformans range from those in an asymptomatic state to systemic disease, especially in immunocompromised hosts. Laryngeal cryptococcal infections are extremely rare-only 7 cases have been reported in the literature. We present a case of cryptococcal laryngitis in an 83-year-old male with chronic obstructive pulmonary disease (COPD) and long-term corticosteroid use. The patient was admitted with a 14-day history of dysphagia, hoarseness, respiratory distress, and upper airway obstruction that necessitated tracheostomy. After intensive respiratory care and fluconazole treatment, his symptoms improved.