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Surgical Treatment of Metastatic Pulmonary Tumors

轉移性肺部腫瘤之外科治療

摘要


轉移腫瘤切除術已證實是對於肺部轉移腫瘤的治療方式之一。為了研究其結果及其預後因子,作回溯性研究分析。於1991年至2003年在高雄榮民總醫院,共七十三位患者因肺部轉移腫瘤接受外科性治療。五年存活率為25.1%,手術死亡率為2.74%。在預後因子統計分析中發現,就病患性別、原發腫瘤種類、手術方式、肺部轉移腫瘤數目、腫瘤大小,對手術後生存並無影響。而原發腫瘤切除治療後至出現肺臟轉移時間小於或大於36個月之五年存活率分別為10.5%及29.6%。原發腫瘤切除治療後至出現肺臟轉移時間為一個重要預後因子。同時轉移腫瘤切除術是安全且有治癒可能的方法。

並列摘要


Background: Metastasectomy has been proved to be an opportunity for long-term survival for patients with various neoplasms with pulmonary metastases. A retrospective study was performed to analyze the results and identify the prognostic factors of surgical treatment for pulmonary metastases. Methods: From 1991 to 2003, a total of 73 patients who underwent surgical treatment for pulmonary metastases at the Kaohsiung Veterans General Hospital were enrolled for analysis. Results: The overall 5-year survival rate was 25.1%. The operation-related mortality rate was 2.74%. Gender, origins of the primary cancers, number of pulmonary metastases, and surgical procedures had no significant effect for those patients who underwent pulmonary metastasectomies. However, patients who had a disease-free interval longer than 36 months had a better 5-year survival rate than those who had a shorter disease-free interval (29.6% vs. 10.5%). Conclusion: Pulmonary metastasectomy is a safe and potentially curative procedure. The disease-free interval is an important prognostic factor for patients with pulmonary metastases.

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