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Pulmonary Nocardiosis Diagnosed by Bronchoalveolar Lavage in a Patient with Hodgkin's Disease after Peripheral Blood Stem Cell Transplantation-A Case Report

支氣管肺泡灌洗術診斷肺Nocardiosis在一周邊血液幹細胞移植後病患-病例報告

摘要


我們診斷了一位罕見的病例-Pulmonary Nocardiosis。這位24歲女性是位因Hodgkin's disease接受周邊血液幹細胞移植的病患,病發時胸部X光片所見是兩側肺出現浸潤性病灶。經由支氣管肺泡灌洗術檢查,在灌洗液細胞學抹片發現了Nocardia菌。經過靜脈trimephoprim-sulfamethoxazole治療19天之後,肺部病灶幾乎完全消解。高度懷疑是診斷肺Nocardiosis最重要的因素。

並列摘要


We experienced a rare case of pulmonary nocardiosis in a 24-year-old female patient with Hodgkin's disease after allogenic peripheral blood stem cell transplantation. The lesions presented as bilateral pulmonary infiltrations on chest radiographs. The Nocardia bacilli were identified in cytological smears of bronchoalveolar lavage fluid obtained from the left lingual lesion. The patient responded well to trimephoprim-sulfamethoxazole (TMP/SMX) and the lesions resolved 19 days after treatment. A high index of suspicion is mandatory for an early diagnosis.

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