- 期刊
Obstructive Sleep Apnea in an Obese Patient with Diabetes Mellitus: A Case Report
罹患阻塞性睡眠呼吸中止症的肥胖糖尿病病患：一病例報告
摘要
睡眠呼吸中止症可加速代謝性異常的原因有可能是因為壓力性荷爾蒙與細胞激素如腎上線皮質醇，介白素6 (IL-6)和腫瘤壞死因子α(TNFα)的持續上升所造成。再者，白天昏睡除了睡眠異常呼吸之外，常與肥胖、糖尿病與胰島素抗性相關。我們在此報告一位罹患阻塞性睡眠呼吸中止症的肥胖糖尿病病患到院求助減重的個案。他被診斷為罹患阻塞性睡眠呼吸中止症(OSA)，併經懸壅垂顎咽整形術與扁桃腺切除術。經開刀後，他減重成功，而且血糖也控制的很好。因此OSA有可能是造成這名病患血糖過高與肥胖的原因。
並列摘要
Sleep apnea may accelerate metabolic abnormalities, possibly through progressive elevation of stress hormones and cytokines such as cortisol, IL-6 and TNFα. Furthermore, daytime sleepiness is frequently associated with obesity, diabetes, and insulin resistance, independently of sleep disordered breathing. We herein report an overweight patient with diabetes mellitus who sought help with weight reduction. He was diagnosed with obstructive sleep apnea (OSA), and an uvulopalatopharyngoplasty (UPPP) and tonsillectomy was performed. He experienced significant weight reduction and normalization of blood sugar after the operation. OSA may have been a possible cause of hyperglycemia and obesity in this patient.
延伸閱讀
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