Flexible Bronchoscopy-Guided, Self-expandable, Metallic Stents Improve Survival in Patients with Esophageal Cancer Complicated with Esophago-Respiratory Fistula

軟式支鏡導引放置呼吸道支架於食道癌併食道－氣管廔管可延長存活

陳資濤(Tzu-Tao Chen) ； 王志冉(Chih-Jan Wang) ； 林啟嵐(Chii-Lan Lin) ； 李俊年(Chun-Nin Lee) ； 劉興璟(H-Eugene Liu) ； 張志誠(Chih-Cheng Chang)

《胸腔醫學》 25卷6期 (2010/12) Pp. 286-293

https://doi.org/10.29806/TM.201012.0001

摘要

Background: Esophago-respiratory fistula, which develops in some esophageal cancer patients, is a devastating and life-threatening complication. When patients are in serious condition, general anesthesia, rigid bronchoscopy and subsequent silicone stent implantation are not feasible. Airway stent implantation can seal the fistula and avoid further complications, such as repeated aspiration. The aim of our study was to evaluate the outcome of airway stent implantation in esophageal cancer patients with esophago-respiratory fistula.
Patients and Methods: From April 2002 to October 2009, 16 consecutive patients with esophago-respiratory fistula-associated esophageal cancer were reviewed. Nine patients received airway stent implantation and 7 did not. The outcomes evaluated included emergency department visit episodes, pneumonia episodes, total hospitalized days due to pneumonia, and days of survival after fistula diagnosis.
Results: The days of survival after fistula diagnosis were significantly different between the airway stent implantation group and the group without an airway stent implantation (80.22±55.14 versus 32.71±70.86, p＜0.05). The other outcomes were not statistically different between the 2 groups.
Conclusions: Airway stent implantation improves the number of days of survival in patients with esophageal cancer complicated with esophago-respiratory fistula.

關鍵字

食道癌 ； 食道－氣管廔管 ； 呼吸道支架

並列摘要

Background: Esophago-respiratory fistula, which develops in some esophageal cancer patients, is a devastating and life-threatening complication. When patients are in serious condition, general anesthesia, rigid bronchoscopy and subsequent silicone stent implantation are not feasible. Airway stent implantation can seal the fistula and avoid further complications, such as repeated aspiration. The aim of our study was to evaluate the outcome of airway stent implantation in esophageal cancer patients with esophago-respiratory fistula.
Patients and Methods: From April 2002 to October 2009, 16 consecutive patients with esophago-respiratory fistula-associated esophageal cancer were reviewed. Nine patients received airway stent implantation and 7 did not. The outcomes evaluated included emergency department visit episodes, pneumonia episodes, total hospitalized days due to pneumonia, and days of survival after fistula diagnosis.
Results: The days of survival after fistula diagnosis were significantly different between the airway stent implantation group and the group without an airway stent implantation (80.22±55.14 versus 32.71±70.86, p＜0.05). The other outcomes were not statistically different between the 2 groups.
Conclusions: Airway stent implantation improves the number of days of survival in patients with esophageal cancer complicated with esophago-respiratory fistula.

並列關鍵字

esophageal cancer ； esophago-respiratory fistula ； airway stent