An Uncommon Lobar Consolidation of Cryptococcal Pneumonia in an Immunocompetent Host: Case Report and Literature Review

罕見大葉性隱球菌肺炎在免疫正常患者的臨床表現病例報告及文獻回顧

郭仲華(Chung-Hua Kuo) ； 王家弘(Jia-Horng Wang)

《胸腔醫學》 26卷1期 (2011/02) Pp. 39-45

https://doi.org/10.29806/TM.201102.0007

摘要

Lobar consolidation of cryptococcal pneumonia is rarely reported in immunocompetent hosts. We report a healthy 25-year-old woman who presented with pneumonia in her left lower lobe. A poor response to empiric antibiotics was noted, and a subsequent investigation disclosed high titers of serum cryptococcal antigen (CSA titer ＞1:1024). Gomori-methenamine silver staining of bronchoalveolar lavage fluid disclosed cryptococci with a cryptococcal antigen titer of 1:128. The patient's symptoms improved with resolution of the consolidation of the left lower lobe of the lung after treatment with fluconazole. We also reviewed the literature.

關鍵字

隱球菌肺炎 ； GMS銀染色 ； 免疫健全

並列摘要

Lobar consolidation of cryptococcal pneumonia is rarely reported in immunocompetent hosts. We report a healthy 25-year-old woman who presented with pneumonia in her left lower lobe. A poor response to empiric antibiotics was noted, and a subsequent investigation disclosed high titers of serum cryptococcal antigen (CSA titer ＞1:1024). Gomori-methenamine silver staining of bronchoalveolar lavage fluid disclosed cryptococci with a cryptococcal antigen titer of 1:128. The patient's symptoms improved with resolution of the consolidation of the left lower lobe of the lung after treatment with fluconazole. We also reviewed the literature.

並列關鍵字

cryptococcal pneumonia ； Gomori-methenamine stain GMS ； immunocompetent