Pulmonary mucoepidermoid carcinoma is a rare disease with a common presentation as an intraluminal mass leading to airway obstruction. We reported a 26-year-old woman who suffered from hemoptysis during or a few days before every menstrual period, and spontaneous pneumothorax. The initial clinical impression was thoracic endometriosis syndrome due to the presence of catamenial hemoptysis. However, computed tomography revealed a suspicious mass-like lesion in the left main bronchus and bronchoscopy confirmed the presence of an endobronchial tumor. She underwent sleeve bronchial resection of the tumor and pathological examination revealed low-grade mucoepidermoid carcinoma. She had an uneventful recovery and was continuously followed in our clinic. For patients presenting with catamenial hemoptysis, endobronchial tumor should be considered, in addition to thoracic endometriosis syndrome.