Proton-Beam Therapy: Present Status and Potential

James M. Slater

《放射治療與腫瘤學》 1卷4期 (1994/12) Pp. 373-381

https://doi.org/10.6316/TRO/199401(4)373

並列摘要

Protons have demonstrated that they are effective for medical use. They are effective because: 1) their mass and charge provide three- dimensional controllability that more nearly approaches the ideal clinical distribution than photons or electrons; 2) they have a favorable and familiar radiobiologic effect; and 3) it is technically feasible to accelerate and deliver protons in a hospital-based facility. Loma Linda University Medical Center, working with scientists, government officials and industries worldwide, demonstrated that feasibility by building and operating a proton-beam delivery system in a health-care setting. Scientists from particle-physics laboratories, universities and industries cooperated to produce a conceptual design for accelerating and transporting 70-250 MeV protons in a facility dedicated to patient treatments. Three 360 rotating gantries and two fixed horizontal beam lines deliver proton beams from any angle while the patient is precisely and comfortably immobilized. A dedicated research room, with three beams, also exists. Clinical operation began in October 1990; by July 1, 1994, nearly 1000 patients had completed treatment and several investigative protocols were underway.