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摘要


自1988年1月至1993年10月,共有45位經組織病理切片證實之腦部惡性神經膠瘤患者於本科接受術後放射線治療。本文分析相關之預後因子,發現術前之病灶爲單一或多發,手術範圍,及術後之行爲狀態(Karnofsky performance status)皆會影響治療之預後。而治療之結果第三級惡性神經膠瘤(退化星細胞瘤)之中值存活期為11.9個月,第四級惡性神經膠瘤(多形神經膠母細胞瘤)之中值存活期為11.5個月。

並列摘要


From January 1988 to October 1993, forty-five patients with histologically confirmed intracranial malignant gliomas were treated with post-operative radiation therapy in our department. They were subjected to this analysis according to the extent of surgery, postoperative Karnofsky performance status, age, histology grading, sex, radiation doses, and presence or absence of seizures. There were 26 males and 19 females between 11 and 67 years of age. The median survival for patients with anaplastic astrocytoma and glioblastoma multiforme was 11.9 and 11.5 months, respectively. The postoperative Karnofsky performance status, extent of surgery, and the multiplicity of lesions were identified as significant prognostic factors.

延伸閱讀


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