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Occult Breast Cancer Presenting as Axillary Nodal Metastases-A Case Report and Review of the Literature

隱性乳癌以腋下淋巴結轉移為表現-病例報告及文獻回顧

摘要


我們報告一位53歲女性病人以腋下淋巴結轉移來表現原發位置不明的乳癌。起初的症狀為右邊腋下腫痛,但乳房並沒有觸摸到腫塊。乳房攝影沒有發現乳房內腫塊,只有呈現右腋下多處高緻密度的淋巴結。正子掃描檢查結果為右邊腋下及右邊鎖骨上淋巴結陽性顯影。經過細胞穿刺檢查後,確定淋巴腺的細胞型態為轉移性的腺癌,雌激素接受體與黃體激素接受體皆為陽性。以上資料顯示病人有原發位置不明之乳癌。病人在接受過右腋下淋巴結清除手術及化學治療後,再繼續接受右乳及右鎖骨上淋巴區的放射治療。病人在治療後追蹤,情況穩定。

並列摘要


We report a case of a 53-year-old female with occult breast cancer presenting with right axillary lymph nodes metastases. The initial presentation was swelling and pain of right axilla without palpable breast mass. Mammography revealed no mass or microcalcification in breast tissue except multiple hyperdense right axillary lymphadenopathy. Positron-emission tomography scan showed increasing FDG uptake of right axillary and right supuraclavicular lymph nodes. Biopsy of lymph node revealed metastatic carcinoma with positive estrogen receptor and progesterone receptor. These data suggested an occult cancer of the breast with right axillary lymph nodes metastases. The patient received right axillary lymph nodes dissection followed by chemotherapy with lipodox and taxotere. Adjuvant radiotherapy to the right breast and right supraclavicular area was given. The patient is well without evidence of disease after the treatment.

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