18F-FDG PET/CT Images Produced Stunningly False-Negative Results after Definitive Chemoradiotherapy in Nasopharyngeal Caricinoma-A Case Report

正子攝影顯示鼻咽癌接受根治性化學放射治療後的擊昏效應影像－個案報告

林詠翔(Yung-Hsiang Lin) ； 王昱豐(Yuh-Feng Wang) ； 徐大聞(Ta-Wen Hsu) ； 邱文彥(Wen-Yen Chiou) ； 李文星(Moon-Sing Lee) ； 林宏益(Hon-Yi Lin) ； 莊紫翎(Tzyy-Ling Chung) ； 洪世凱(Shih-Kai Hung)

《放射治療與腫瘤學》 18卷2期 (2011/06) Pp. 157-161

https://doi.org/10.6316/TRO/201118(2)157

摘要

我們報告了一位45歲鼻咽癌男性，接受根治性化學放射治療三個月之後，核磁共振的檢查顯示有多顆殘存頸部淋巴結，可是正子攝影並無明顯活性吸收。我們安排了改良式頸部淋巴廓清術之後，證明頸部淋巴結是經由鼻咽轉移來的惡性細胞。正子攝影呈現即使根治性治療後超過3個月，仍可能出現擊昏效應影像。在短時間的根治性治療後，功能性的檢查仍需謹慎小心。

關鍵字

鼻咽癌 ； 正子攝影 ； 擊昏效應

並列摘要

We report the case of a 45-year-old man who received definitive chemoradiotherapy for nasopharyngeal carcinoma. Three months after chemoradiotherapy, head-and-neck magnetic resonance imaging (MRI) showed multiple residual lymph nodes with what appeared to be metastases in the neck. However, 18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) produced nonspecific findings. We performed a confirmatory modified radical neck dissection; and pathologic examination revealed metastatic carcinoma, consistent with nasopharyngeal origin. The dramatic false-negative results were obtained on FDG-PET images more than 3 months after chemoradiotherapy. We conclude that functional studies need to be interpreted with caution within short intervals after definitive chemoradiotherapy even after 3 months.

並列關鍵字

18-fluoro-2-deoxyglucose positron emission tomography FDG-PET ； Nasopharyngeal carcinoma ； Stunning effect