- 期刊
利用放射線治療默克細胞癌淋巴腺轉移的病患－病例報告
Radiotherapy for Merkel Cell Carcinoma with Lymph Node Metastasis: A Case Report
摘要
默克細胞癌（Merkel cell carcinoma; MCC）是一種罕見的原發性皮膚神經內分泌腫瘤，其預後差存活率也低，在美國發病率估計3.2～4.4人／每百萬人－年。通常MCC的病程發展快速，早期局部復發和遠處轉移率高達25%，MCC好發於65歲以上的老人，發病位置大多為暴露在陽光下的頭頸部區域約佔55%，40%在四肢和5%在軀幹。在本篇報告中提出了一名75歲於2008年在本院治療pT3bNO stage III的前列腺癌，2012年又在右側耳前區發現TXN1MO stage IIIB的MCC的病患。術後接受劑量為61.2 Gy的放射治療，文獻回顧表示積極的化放療司以提高局部控制率和生存率。
並列摘要
Merkel cell carcinoma (MCC) is a rare primary cutaneous tumor of neuroendocrine type associated with a poor prognosis and a low survival rate. It has an estimated age-adjusted incidence of 3.2 to 4.4 per 1,000,000 person-years in the United States. MCC usually has an aggressive course with early locoregional recurrence and high distant metastatic rates of up to 25% in most series. It usually affects elderly people over 65 years of age. It preferably affects areas exposed to the sun: 55% in the head and neck, 40% in the limbs and 5% in the trunk. Here we present a 75 year old case of cT0 pNl cMl stage IV Merkel cell carcinoma of right preauricular area with pT3bNO, stage III prostate cancer. Postoperative radiotherapy was given to the patient for 61.2 Gy. A literature review of MCC indicates that aggressive radiotherapy can have a positive impact on overalllocal control and survival.
延伸閱讀
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