- 期刊
口腔癌術後放射線合併化學治療誘發之急性骨髓性白血病－病例報告
Therapy-Related Acute Myeloid Leukemia Following Chemoradiotherapy in Oral Squamous Cell Carcinoma-A Case Report
摘要
口腔癌術後的放射及化學治療主要目的在於改善病人的預後，雖然這些輔助治療的確能夠提高病人的存活率，但偶有報告指出現行的拼音後輔助治療可能導致繼發性惡性腫瘤的產生。本報告提出一位59歲男性患者，因罹患第一期的口腔癌，在腫瘤手術切除後接受放射以及口服化學藥物UFUR的治療，術後復原、狀況良好且無口腔為復發的狀況，卻在後續追蹤3個月時罹患急性骨髓性白血病，合併多重器官衰竭而死亡的病例。
並列摘要
The purpose of postoperative adjuvant therapy is to improve the prognosis in oral cancer patients. Although chemoradiotherapy raises the survival rates indeed, there are few reports which show parts of modem anti-cancer drugs may relate the seoondary malignancy. Here we report a case of therapy-related acute myeloid leukemia in a 59 y/o man who was a victim of oral squamous cell carcinoma. After operation and chemoradiotherapy, he remained disease free for 3 months while continuing on a daily regimen of UFUR. However, he was diagnosed with acute myeloid leukemia after a 3-months follow-up. He died of leukemiainduced multiple organ failure within 1 week after the diagnosis of leukemia.
延伸閱讀
- Wu, C. H., Lee, C. H., Lin, H. W., & Kuo, Y. S. (2022). 放射線治療誘發之口腔肉瘤與肉瘤樣癌－二病例報告. 臺灣口腔顎面外科學會雜誌, 33(4), 265-274. https://www.airitilibrary.com/Article/Detail?DocID=a0000494-202212-202212160014-202212160014-265-274
- Lai, Y. M., Chao, T. K., Tseng, F. F., & Chen, Y. W. (2022). 以手術切除同步併用化學放射療法與客製化標靶藥物治療多發性口腔癌－病例報告. 臺灣口腔顎面外科學會雜誌, 33(2), 125-136. https://www.airitilibrary.com/Article/Detail?DocID=a0000494-202206-202207140005-202207140005-125-136
- Chen, L. C., Hung, S. K., Lee, M. S., Chiou, W. Y., Shen, B. J., Shih, Y. T., Hsu, F. C., Tsai, W. T., Lin, Y. A., Hsieh, H. L., Lin, P. H., Kuo, H. Y., & Lin, H. Y. (2016). 口腔癌病人合併無法切除之肺寡量轉移病灶接受「立體定位燒灼性」及「同步腫瘤內增量」放射治療：一個病例報告. 放射治療與腫瘤學, 23(3), 191-203. https://doi.org/10.6316/TRO/201623(3)191
- Hung, J. W., Kuo, C. Y., & Leong, C. P. (1999). Sphincter Disturbance as the Initial Presentation of Acute Lymphoblastic Leukemia：A Case Report. 中華民國復健醫學會雜誌, 27(1), 31-36. https://www.airitilibrary.com/Article/Detail?DocID=10253009-199903-27-1-31-36-a
- Yu, K. P., Hwang, W. S., Lee, W. C., Lin, J. S., & Twu, B. H. (1985). Priapism in Patients with Chronic Myeloid Leukemia: Report of Two Cases. Journal of Medical Sciences, 6(1), 87-91. https://www.airitilibrary.com/Article/Detail?DocID=10114564-198507-201404230009-201404230009-87-91