The economic reforms and the widespread implementation of market socialism in Chinese society, as the economic reforms have unfolded and they have been accompanied by significant changes in the health care system. In general, the people demanded for improving in health status and greater access to health care. It is an important issue that hospitals adopt external resource to improve health care delivery in the reform era. The primary purpose of the paper is to contribute to a concept of the framework that address the driving factors of outsourcing from the cost, resource-based, and organizational change perspectives of the health care organizations. Meanwhile, this paper illustrates that institutional factors and agency factors have caused outsourcing obstacles and problems in the outsourcing strategy. A case study approach was adopted with primary data collected through in-deep interview with six hospitals in China and secondary data aggregated from hospital documents and website. This paper presents a systematic exploration of the drivers and obstacles of outsourcing in China, and provides a framework that may guide health care organizations to develop strategic outsourcing plans, and to achieve outsourcing objectives.