Purpose:The purposes of the study were: 1) to use Taiwan's National Health Insurance Reseach Database (NHIRD) related to the presciptions of oral hypoglycemic agents (OHAs) for analyzing if medication therapy is consistent with diagnosis; 2) to explore the relationship between diagnosis and medication therapy in various professional levels; and 3) to investigate if inconsistency among medications is same.Material and Methods:A long-term retrospective study was implemented to use NHIRD between January 1998 and December 2007. The unit of analysis was each OHA prescription without diagnosis codes of diabetes mellitus (DM). The study observation was described as inconsistent prevalence.Results and Discussion:There were 5,221,072 outpatients' prescriptions collected in this study, and 2,557 inconsistent prescriptions in 238,768 OHAs prescriptions were observed. The mean inconsistent prevalence is 1.07%. The prevalence of clinic in general, internal medicine and special internal medicine was respectively 2.45%, 1.37% and 0.52% (P<.0001). In special internal medicine, the prevalences of cardiology, gastroenterology, nephrology and endocrinology were 1.27%, 0.94%, 0.71% and 0.12% (P<.0001), respectively. Endocrinology is the professional of DM, therefore it could be found more professional is more consistent between diagnosis and medication therapy. It also implied that potential medication errors were less happened in professional clinics. In OHAs, the prevalence was individually for biguanides 0.73%, sulfonylureas 1.62%, alpha glucosidase inhibitors 0.45% and thiazolidinediones 0.16% (P<.0001). The sulfonylureas with higher risk of hypoglycemia provided higher inconsistent prescriptions among OHAs to assume more potential prescribing errors. For high-alert medications, the consistency between diagnosis and medication therapy should be carefully examined in the healthcare system.
Purpose:The purposes of the study were: 1) to use Taiwan's National Health Insurance Reseach Database (NHIRD) related to the presciptions of oral hypoglycemic agents (OHAs) for analyzing if medication therapy is consistent with diagnosis; 2) to explore the relationship between diagnosis and medication therapy in various professional levels; and 3) to investigate if inconsistency among medications is same.Material and Methods:A long-term retrospective study was implemented to use NHIRD between January 1998 and December 2007. The unit of analysis was each OHA prescription without diagnosis codes of diabetes mellitus (DM). The study observation was described as inconsistent prevalence.Results and Discussion:There were 5,221,072 outpatients' prescriptions collected in this study, and 2,557 inconsistent prescriptions in 238,768 OHAs prescriptions were observed. The mean inconsistent prevalence is 1.07%. The prevalence of clinic in general, internal medicine and special internal medicine was respectively 2.45%, 1.37% and 0.52% (P<.0001). In special internal medicine, the prevalences of cardiology, gastroenterology, nephrology and endocrinology were 1.27%, 0.94%, 0.71% and 0.12% (P<.0001), respectively. Endocrinology is the professional of DM, therefore it could be found more professional is more consistent between diagnosis and medication therapy. It also implied that potential medication errors were less happened in professional clinics. In OHAs, the prevalence was individually for biguanides 0.73%, sulfonylureas 1.62%, alpha glucosidase inhibitors 0.45% and thiazolidinediones 0.16% (P<.0001). The sulfonylureas with higher risk of hypoglycemia provided higher inconsistent prescriptions among OHAs to assume more potential prescribing errors. For high-alert medications, the consistency between diagnosis and medication therapy should be carefully examined in the healthcare system.