摘要
暫時性新生兒膿疱性色素沉著症為一少見之皮膚疾病，特徵為出生時出現短暫之膿疱病灶，隨後膿疱破裂形成色素斑。此病在台灣盛行率未知，吾人報告一新生兒病例，病嬰出生時便在臉上及軀幹處出現數個鬆弛性膿疱，所有實驗室檢查，包括細菌及黴菌培養，均呈陰性結果，組織鏡檢下顯示一表皮內形成之水疱，內含多數中性白血球及少量嗜伊紅性血球。病灶於第六天自行消褪，少數形成色素沉著現象，二週後，此色素沉著變化亦自行消失，據吾人所知，此乃台灣第一例病例報告。
關鍵字
無資料並列摘要
Transient neonatal pustular melanosis (TNPM) is a relatively rare dermatosis characterized by a short duration of pustular lesions, which then evolve into macular hyperpigmentation. Its prevalence is unknown in Taiwan. We report a newborn baby boy with skin manifestations that showed several flaccid pustules on face and trunk at birth. All laboratory studies, including bacterial and fungal culture, revealed negative results. Histopathologically, an intraepidermal vesicle containing predominantly neutrophils and very few eosinophils was noted. The pustules fade away spontaneously by day 6 after birth with some hyperpigmented change. Two weeks later, the discoloration regressed without treatment. To our knowledge, this is the first reported case in Taiwan.
延伸閱讀
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