以離電子泳法減緩蟹足腫注射所引起之疼痛

蟹足腫是一種癒合過程中良性的真皮纖維組織過度增殖，好發於具特異體質患者身上，病灶內注射膽固醇是常被使用的有效治療之一。然而，注射過程中所合併之疼痛常使病人裹足不前。我們嘗試以lidocaine離子電泳法來減輕注射所引起之疼痛。共10位女性病人接受此法，年齡分佈為20歲到45歲〈平均28歲〉，利用離子導入儀器〈Novel Corona type RH-3,日本製〉，將含2%lidocaine及epinephrine 1/80,000溶液〈Xylocaine, Fujisawa Pharmaceutical Co., Japan〉，以1毫安培的電流，經皮導入30分鐘，再進行病灶內注射膽固醇，病人依自覺疼痛程度評分〈由輕至重分別為0至10分〉，過程中，僅一位病人手握負極之指頭發生電燙傷，餘無其他副作用。所有接受離子電泳法的病人皆得到明顯的疼痛握解，疼痛分數有顯著差異〈中位數為1：7，治療組：對照組，p＜0.01, Wilcoxon-signed rank test〉，我們認為在進行病灶內注射類固醇治療蟹足腫前，施行lidocaine離子電泳法是一種安全且有效的局部麻醉方法，可達滿意的疼痛緩解。

關鍵字

無資料

並列摘要

Keloid is a benign over-growth of dermal fibrous tissue during wound healing in predisposed individuals. Though intralesional steroid injection is one of the common effective treatments, many patients were reluctant to this treatment because of the associated pain. We overcome this problem by using lidocaine iontophoretic local anesthesia before injection. Ten female keloid patients, ages ranging from 20 to 45 years (mean 28 years) were enrolled. Two percent lidocaine with 1/80,000 epinephrine was transdermal iontophoretic delivered with an iontophoresis apparatus (Novel Corona type RH-3, Japan) at 1mA for 30 minutes before intralesional injection . Pain associated with injection was assessed with a pain score, which was graded by the patient with a visual analog scale from 0 to 10 in ascending severity. No side effect was noted except one patient had electric burn on her finger holding the electrode. The median of Pain score was 1 in patients underwent the procedure while 7 in the control group (p＜0.01, Wilcoxon-signed rank test). We conclude that lidocaine iontophoretic local anesthesia can lessen the painful injection of triamcinolone acetonide in treating keloid patients.

並列關鍵字

Keloid ； Intralesional triamcinolone acetonide injection ； Lidocaine ； Iontophoresis

國際替代計量

以離電子泳法減緩蟹足腫注射所引起之疼痛

未授權

主題瀏覽