摘要
一位三十歲的臺灣男性，在軀幹和四肢表現出廣泛性棕黑色的丘疹和板塊，已有七年。理學檢查發現病人有全身性的淋巴結腫大。其皮膚切片顯示在真皮層有許多成熟的漿細胞浸潤。免疫組織化學檢查發現這些漿細胞都是多株性的，而免疫球蛋白重鏈基因重排檢查排除了淋巴瘤的可能性。此病人並無自體免疫疾病或任何感染的證據。他同時有IgA腎病變和多株性的旭瑪蛋白球血症。這種罕見的情況在日本的文獻中曾被報告為皮膚漿細胞增生症。我們報告一例這種病症的臨床病理表現，證明皮膚漿細胞增生症也發生在臺灣。
關鍵字
無資料並列摘要
A 30-year-old Taiwanese man presented with wild spread brown-black papules and plaques on His trunk and extremities for 7 years. Physical examination showed generalized lymphadenopathy. A skin biopsy specimen revealed dermal infiltrates of many mature plasma cells. The immunohistochem- ical study showed polyclonal origin of the plasma cells, and the immunoglobulin heavy chain gene rearrangement study excluded the possibility of lymphoma.there was no evidence of autoimmune disease or any infection sign. The patient also had IgA nephropathy and polyclonal hypergammaglob- ulinemia. This unusual condition has been reported as cutaneous plasmacytosis in Japanese literature. The clinicopathologcial features of this entity are described to document its occurrence in Taiwan.
延伸閱讀
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