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Erythema Nodosum Associated with Active Cytomegalovirus Infection

結節性紅斑合併巨細胞病毒感染

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摘要


結節性紅斑與非常多的疾病有關,尋找可能的致病因對於結節性紅斑的處理有很大的幫助。大部份的成年人都已經被巨細胞病毒感染過,通常是沒有臨床症狀的。免疫健全的人很少會表現出巨細胞病毒感染的皮膚表徵。我們報告一個結節性紅斑合併活化的巨細胞病毒感染的罕見病例。一40歲的女性兩側下肢出現數顆疼痛的結節。幾天後病人也出現了發燒和喉嚨痛的症狀。病毒學的研究顯示抗巨細胞病毒抗體IgM 和IgG 皆呈現出陽性反應。以口服抗病毒藥ganciclovir治療兩週之後成功地解除了發燒及下肢結節疼痛的症狀。(中華皮誌22 : 129-133 , 2004 )

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並列摘要


Erythema nodosum is associated with a wide variety of diseases, and searching for the underlying etiology is important for management of the disease. Most adults have already been infected by cytomegalovirus (CMV), often subclinically and asymptomatically. Immunocompetent individuals very rarely present with cutaneous manifestations of CMV infection. We report a rare case of erythema nodosum associated with active CMV infection. A 40- year - old female presented with several tender nodules over the extensor surface of bilateral lower legs. A few days later, the patient also presented with the symptoms of fever and sore throat. Virological survey revealed anti - CMV antibodies 1gM and IgG were both positive. Two weeks of therapy with oral ganciclovir successfully relieved the symptoms of fever and painful sensation of the nodules of the legs. (Dermatol Sinica 22: 129- 133, 2004)

並列關鍵字

Erythema nodosum Cytomegalovirus

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