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The Combination of Tripe Palms, Acanthosis Nigricans and Florid Cutaneous Papillomatosis in a Patient with Metastatic Cervical Cancer

轉移子宮頸癌病人合併牛胃掌、黑棘皮症及密集性皮膚乳突瘤

摘要


牛胃掌(tripe palms)意指手掌處的皮膚變厚、掌紋變深並顯現天鵝絨般的質感。大多數典型牛胃掌都是伴腫瘤性的皮膚變化,尤其源於上消化呼吸道的癌症。黑棘皮症及密集性皮膚乳突瘤是最常伴隨的皮膚病變,它們可能代表者同一個病因在不同部位的皮膚的表現。因此對所有牛胃掌或密集性皮膚乳突瘤的病人,都需要有完整的癌症篩檢。我們報告一例五十五歲女性,因手腳皮膚變厚就診,經診斷為牛胃掌,伴隨黑棘皮症及密集性皮膚乳突瘤等皮膚病變,我們進一步發現患者體內的子宮頸癌已呈現復發及廣泛性的轉移。(中華皮誌22 : 142-147 , 2004 )

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並列摘要


Tripe palms, which described the thickening of pamar skin with increase of normal dermatoglyphics and a peculiar velvety texture, is a specific cutaneous paraneoplastic syndrome especially related to cancers of upper aerodigestive tract. Acanthosis nigricans, and florid cutaneous papillomatosis (sudden appearance of many warty skin lesions) are the most commonly associated paraneoplastic dennatosis. All three may be part of a continuum, caused by factors produced by the underlying malignancy. A thorough investigation for an underlying malignancy is warranted for all patients with tripe palms and/or florid cutaneous papillomatosis. We reported a 55-year-old female initially presented with tripe palms. After detailed cutaneous survey, acanthosis nigricans and florid cutaneous papillomatosis were also found. Thorough examinations revealed recurrence and metastasis of her cervical cancer. (Dermatol Sinica 22: 142-147, 2004)

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