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Malignant Schwannoma with a Rhabdomyoblastic Component a So-Called Malignant "Triton" Tumor: Report of a Case and Review of Literature

惡性神經髓鞘瘤合併橫紋肌胚瘤分化(惡性蠑螈瘤):病例報告及文獻覆閱

摘要


惡性神經髓鞘瘤合併橫紋肌胚瘤的分化,稱為惡性蠑螈瘤,最早在1932年由Masson所處出,到目前為止在英文文獻記載上,僅有38例報告,本文報告此一罕見的惡性瘤,除討論其組織成因及組織病理上的特徵外,並覆閱文獻所報告的病例。

關鍵字

惡性蠑螈瘤

並列摘要


Malignant ”Triton” tumor, malignant schwannoma with a rhabdomyoblastic differentiation, are rare. There only 38 cases have been previously reported in the English journal. We herein report an additional case, a 41-year-old man with Von-Recklinghausen's Neurofibromatosis(VRN) with a tumor mass over the right buttock region for more than 10 years. We also use the immuno peroxidase staining for the schwann's cell marker S-100 protein and for the skeletal muscle proteins actin and myoglobin to elucidate the histopathologic characteristics of this malignant tumor. The literatures about histopathogenesis and prognosis are also reviewed.

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