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Tuberculous Gumma (Cutaneous Metastatic Tuberculous Abscess)

結核腫(皮膚轉移性結核膿瘍)

摘要


結核腫,又叫做皮膚轉移性結核膿瘍,是一種多菌型,由原發病灶血行傳播所造成的皮膚結核。我們報告一個位於右脛前的結核腫案例。一位38歲的女性,患有肺部粟粒狀結核及非霍傑金氏淋巴瘤,被發現在右脛前出現一鴿蛋大小的軟結節。病理檢查可見肉芽腫性發炎併有少量的巨大細胞,及在深部真皮及皮下組織大量的發炎細胞浸潤。同時,也發現嚴重的壞死及膿瘍。Acid-fast染色發現多數染色陽性的桿菌。組織的增減長出結核分枝桿菌。病人接受前兩個月每日rifampin,isoniazid,pyrazinamide以及ethambutol的治療以及之後四個月rifampin和isoniazid的治療。病人至今無皮膚病灶複發。

關鍵字

無資料

並列摘要


Tuberculous gumma, also called metastatic tuberculous abscess, is a multibacillary type of skin tuberculosis caused by hematogenous spread of mycobacteria from a primary focus. We report a patient with tuberculous gumma on the right shin. The 68-year-old woman with pulmonary miliary tuberculosis and an occult non-Hodgkin lymphoma was found to have a pigeon-egg sized, soft nodule on the right shin. Histopathologic examination showed granulomatous inflammation with occasional giant cells and a pronounced inflammatory infiltrate in the deep dermis and subcutaneous tissue. Extensive necrosis with abscess formation was also noted. Acid-fast stain revealed multiple acid-fast bacilli. The tissue culture yielded Mycobacterium tuberculosis. The patient was treated with rifampin, isoniazid, pyrazinamide, and ethambutol daily for the initial 2 months, and isoniazid and rifampin for 4 more months. No recurrence of any skin lesion has been noted.

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