- 期刊
Kikuchi's Disease (Histiocytic Necrotizing Lymphadenitis) Associated with Cutaneous Lupus Erythematosus
組織細胞壞死性淋巴病變合併皮膚紅斑性狼瘡
摘要
組織細胞壞死性淋巴病變（Kikuchi's disease，菊池氏病）為一種罕見的以發燒及主要侵襲後頸部單一性或多發性淋巴病變為特徵的臨床疾病。文獻曾報告過菊池氏病發生於系統性紅斑性狼瘡之前，或兩者同時存在，或發生於系統性紅斑性狼瘡之後。只有在極少數的病例中，菊池氏病僅與皮膚紅斑性狼瘡合併存在但無任何系統性病灶。我們在此報告二例具有典型菊池氏病症狀的病例，患者於診斷菊池氏病後一至二個月出現皮膚紅斑性狼瘡的病灶。但患者並未符合美國風濕學會對系統性紅斑狼瘡的評分標準(American Rheumatism Association criteria for systemic lupus erythematosus)。我們於此對菊池氏病與皮膚紅斑性狼瘡二者間可能的致病關聯性作一探討。
關鍵字
無資料並列摘要
Histiocytic necrotizing lymphadenopathy (Kikuchi's disease) is a rarely observed clinical entity characterized by fever and solitary or multiple lymphadenopathy predominantly in the posterior cervical region. Kikuchi's disease has been reported to precede, coexist with or follow the diagnosis of systemic lupus erythematosus. In only rare instances has its association with cutaneous lupus erythematosus without systemic involvement been reported. We report two cases who presented with characteristic manifestations of Kikuchi's disease. One to two months later, they developed lesions of cutaneous lupus erythematosus. The American Rheumatism Association criteria for systemic lupus erythematosus were not fulfilled. The possible pathogenic relationships between the two processes are discussed.
延伸閱讀
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