- 期刊
Granulomatous Periorificial Dermatitis in a Young Woman
年輕女性之肉芽腫性口圍皮膚炎
摘要
肉芽腫性口圍皮膚炎是一種大多發生於黑人兒童的皮膚疾患。臨床上的表現為在口、眼、鼻的周圍出現許多細小的丘疹，少數兒童亦同時有臉外的病灶產生。這些病灶多數為自限性且消失後僅有少數會留下疤痕。在此我們報告一位28歲的女性在口、眼、鼻的周圍與上肢於8個月內陸續發生數個1到3公厘、正常膚色至粉紅色、分離或團聚的丘疹。病理下可見真皮內的毛囊旁有肉芽腫產生，內含淋巴球、表皮樣組織細胞以及少數的多核巨大細胞。經投與口服去氧羥四環素以及外用咪唑尼達凝膠二個月後病灶全部消失。
關鍵字
無資料並列摘要
Granulomatous periorificial dermatitis is a skin disease presenting predominantly in prepubertal black-skinned children. It is characterized by tiny, monomorphous, papular eruptions around the mouth, nose and eyes. Extra-facial lesions in children had also been reported. These lesions are self-limited and resolved without scarring in most cases. We report a 28-year-old woman presented with pink to normal skin colored, discrete and coalescing papules ranging from 1 to 3 mm in diameter over the face, nape and bilateral forearms of 8 months duration. A biopsy on the right nasolabial fold showed dermal granuloma formation around hair follicles, composed of lymphocytes, epithelioid histiocytes and occasional multinucleated giant cells. Oral doxycycline and topical metronidazole gel were given and the skin lesions cleared after 2 months treatment.
延伸閱讀
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