Squamous Cell Carcinoma of the Oral Cavity in Young Patients

有許多文獻指出年輕族群之口腔癌病患有增加之趨勢，然而，年輕族群病患之病程與預後是否有特異性仍倍受爭議。本文回顧奇美醫學中心口腔顎面外科自民國84年1月至90年12月間治療過之病患資料，選取271位病患作為研究樣本，其中小於（含）40歲以下之病患共計55人(20.3%)，我們依其性別、不良口腔嗜好、TNM分期、腫瘤分化程度、局部與頸部復發情形、遠處轉移比例、第二原發腫瘤比例、無疾病存活率及整體存活率等來作為比較之項目。結果發現：兩組病患在各項目並未發現有任何統計學上明顯之差異；因此，在本院之資料中確實呈現有較多之年輕族群口腔癌患者，但其並沒有表現出特異之疾病特徵，故我們建議對此族群採取相同之治療策略。

關鍵字

口腔鱗狀上皮細胞癌；年輕族群；無疾病存活；局部與頸部淋巴復發

並列摘要

Background. Irrespective of many increasing frequencies of oral cancer in younger adults announced, there are still controversies concerning the clinical course and outcome of this group. Patients & Methods. The retrospective review of 271 sample patients with previously untreated squamous cell carcinoma of the oral cavity was managed by one of authors in the 8-year period: (1) 55(20.3%) of the patients were aged 40 years or younger; (2) The gender, high-risk oral habits, TNM stage condition, tumor differentiation, locoregional recurrence, distant metastasis, rate of second primary tumor, disease free-survival and overall survival were compared for both populations. Results. For both groups: (1) The sex ratio between younger and older patients was similar; (2) The personal habits noticed no significant difference; (3) The proportion of tumor differentiation, neck lymph node metastasis and TNM stage were similar; (4) The rates of metastatic disease and secondary primary lesions were similar; (5) The 2-year disease-free survival for younger patients was 60% and 53.9% for older population. Conclusion. The results revealed that higher incidence rate of young OSCC in our hospital, the biological behavior of young OSCC was indistinct from that of the older. Therefore, the same treatment strategy for both populations in Taiwan is suggested.

並列關鍵字

Oral squamous cell carcinoma ； Young patients ； Disease-free survival ； Loco-regional recurrence

國際替代計量

Squamous Cell Carcinoma of the Oral Cavity in Young Patients

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