Hailey-Hailey Disease Successfully Treated with Carbon Dioxide Laser-A Case Report

以二氧化碳雷射成功治療家族良性天皰瘡－病例報告

林育全(Yu-Chuan Lin) ； 張中興(Chung-Hsing Chang)

《中華皮膚科醫學雜誌》 25卷2期 (2007/06) Pp. 132-135

https://doi.org/10.29784/DS.200706.0009

摘要

一位四十五歲男性，因腋下、腹股溝及膕窩等對磨部位出現反覆性水泡及潰瘍病變而來求診。病人塗抹類固醇藥膏多年，但病程起伏，皮疹從未完全消失。我們在左邊腋下施行皮膚切片，組織病理檢查顯示在基底細胞層上方有棘層鬆解的現象（崩落的磚牆）。由臨床所見及皮膚組織病理變化顯示這是一個家族良性慢性天皰瘡的病例。我們以二氧化碳雷射治療兩側腋下對藥物反應不佳處之病灶，三週之後，經雷射部位出現新生的表皮。一年之後，經過雷射治療的病灶並無復發之情形。在此我們報告一個以二氧化碳雷射成功治療一頑固家族良性慢性天皰瘡的病例。

並列摘要

A 45-year-old man presented with erythematous vesicles and erosions on erythematous backgrounds on his axillae, groin, and popliteal fossae. He had been treated with corticosteroid ointments for several years, but the clinical course waxed and waned, and the lesions never completely disappeared. A skin biopsy specimen from his left axilla revealed suprabasal acantholysis (a ”dilapidated brick wall”). Diagnosis of recurrent Hailey-Hailey disease was made after careful analysis of the clinical and histopathological features. We administered a CO2 laser to eradicate the unresponsive remnants of the lesion. The operative site re-epithelialized within 3 weeks. One year after the treatment, there was no evidence of recurrence. For recalcitrant cases of Hailey-Hailey disease, as in this case, the use of a CO2 laser may be an effective therapeutic modality.

並列關鍵字

Hailey-Hailey disease ； Familial benign pemphigus ； CO2 laser