異質移植骨與異體移植骨合併引導組織再生術：病例報告

Clinical Evaluation of Allograft (DFDBA) and Xenograft (Bio-Oss) Combined with Bioresorbable Membranes in the Treatment of Intraosseous Defects: Report of Cases

鄭文彥(Wen-Yen Cheng) ； 劉謙美(Cheng-Meei Liu) ； 侯連團(Lein-Tuan Hou)

《中華民國牙周病醫學會雜誌》 6卷1期 (2001/03) Pp. 29-37

https://doi.org/10.6121/CJP.200103_6(1).0005

摘要

本篇臨床觀察研究的目的是要比較冷凍乾燥脫鈣異質移植骨（demineralized freeze-dried bone allograft, DFDBA）及牛骨衍生之異體移植骨（bovine derived xenograft, Bio-Oss®）在合併使用可吸收之再生膜於治療3-wall牙周骨內缺損時的臨床治療效果。三位女性病患在牙周基本治療後仍有3-wall的骨內缺損（intraosseous defect），經翻瓣（flap reflection），軟組織清創（soft tissue debridement）及牙根平整後，於骨缺損處填入DFDBA或Bio-Oss®，再覆蓋可吸收的再生膜，之後將翻瓣縫合。經6個月及一年的臨床觀察，不管在囊袋降低及新骨生成，臨床上都可以得到滿意及穩定的結果。

關鍵字

冷凍乾燥脫鈣異質移植骨 ； 異體移植骨 ； 骨內缺損 ； 可吸收再生膜引導組織再生術

並列摘要

The aim of this study was to compare the results of a demineralized freeze-dried bone allograft (DFDBA) with a bovine-derived xenograft (Bio-Oss®) which were used in combination with bioresorbable membranes in the treatment of human periodontal 3-wall intraosseous defects. Three female patients with intraosseous defects were treated by guided tissue regeneration procedures using implant materials described previously after routine periodontal phase I therapy. The surgical procedures consisted of flap reflection, soft tissue debridements and root planning, then placement into osseous defects of either DFDBA (Pacific coast Tissue Bank) or Bio-Oss® (Osteohealth company). The transplant sites were covered by a bioresorbable membrane and then closed primarily by a intimate flap adaptation. At 6 and 12 months postoperatively, clinical observations demonstrated satisfactory results of both grafting materials in reduction of pocket depth and radiographic bone fill.

並列關鍵字

demineralized freeze-dried bone allograft ； DFDBA ； bovine-derived xenograft ； Bio-Oss® ； intraosseous defect ； bioresorbable membrane ； guided tissue regeneration