Detoxification with Intravenous Drip Short-acting Benzodiazepines in a Zolpidem-dependent Patient with Intolerable Withdrawal Dizziness

以靜脈點滴注射短效型benzodiazepines治療zolpidem依賴病人的嚴重暈眩戒斷症狀

李顓雅(Chuan-Ya Lee) ； 蔡世仁(Shih-Jen Tsai)

《台灣精神醫學》 25卷1期 (2011/04) Pp. 41-44

https://doi.org/10.29478/TJP.201104.0007

並列摘要

Objective: To report a case of physical and psychological addiction to an excessive dose of zolpidem and subsequent completed detoxification using intravenous drip benzodiazepines. Case report: A 30-year-old female patient had high-dose zolpidem dependence with 120 mg-160 mg per day for two years. She suffered from severe withdrawal symptoms including dizziness when she discontinued zolpidem. She experienced more severe dizziness under oral benzodiazepine medication for detoxification. She was later successfully treated with intravenous drip short-acting benzodiazepines for the zolpidem withdrawal symptoms without dizziness adverse effects. Conclusion: Given the similarities in receptor binding and pharmacologic activities of zolpidem and the benzodiazepines, benzodiazepines are commonly used for zolpidem detoxification. Intravenous drip short-acting benzodiazepines may improve the zolpidem withdrawal symptoms without aggravating dizziness symptoms.

並列關鍵字

Intravenous ； benzodiazepines ； zolpidem-dependent ； withdrawal symptoms

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