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Large Cell Neuroendocrine Carcinoma of the Uterine Cervix Associated with Adenocarcinoma

並列摘要


Objective: Large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive cervical neoplasm. In the present study, we present a 45-year-old woman with large cell neuroendocrine uterine cervical carcinoma with coexisting adenocarcinoma. Case Report: A 45-year-old G2 P0 presented with vaginal bleeding for 7 months. On pelvic examination, a polypoid mass of the cervix was discovered. Biopsy of the lesion revealed large cell neuroendocrine carcinoma of the cervix. The patient underwent a radical hysterectomy, and then received concurrent chemotherapy and radiation therapy. She has remained disease free until the time of this writing. Conclusion: Patients with LCNEC of the cervix have had poor prognoses; hence aggressive multimodality treatment is recommended.

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