- 期刊
High-Dose Misoprostol as an Alternative Therapy after Failed Medical Abortion
並列摘要
Objective: The aim of this study was to determine the complete abortion rate for the vaginal administration of high-dose misoprostol after a failed medical abortion. Materials and Methods: When their medical abortions failed after the conventional oral administration of mifepristone and misoprostol, participants then received 1,000 μg of misoprostol vaginally. The efficacy and side effects of this treatment were evaluated. Results: Twenty-seven women who failed to abort after the conventional administration of mifepristone and misoprostol were enrolled in this trial. Fourteen days after the vaginal administration of 1,000 μg misoprostol, the overall complete expulsion rate had reached 88.8% (24/27). Most adverse effects were mild to moderate and did not require treatment. Conclusion: The vaginal administration of 1,000 μg misoprostol as a salvage therapy after a failed medical abortion appears to be a safe and highly effective alternative to surgical intervention.
延伸閱讀
- Lin, M., Li, Y. T., Chen, F. M., Wu, S. F., Tsai, C. W., Chen, T. H., & Kuo, T. C. (2006). Use of Mifepristone and Sublingual Misoprostol for Early Medical Abortion. Taiwanese Journal of Obstetrics & Gynecology, 45(4), 321-324. https://doi.org/10.29787/TJOG.200612.0007
- Li, Y. T., Kuo, T. C., & Chen, F. M. (2003). The Use of Misoprostol to Control Postabortion Uterine Bleeding. Taiwanese Journal of Obstetrics & Gynecology, 42(4), 243-245. https://doi.org/10.29787/TJOG.200312.0004
- 陳國嶸、林隆堯（2003）。RU486 Combined with Oral Misoprostol for Medical Abortion in First-Trimester Pregnant Women。中山醫學雜誌，14(1)，63-70。https://doi.org/10.30096/CSMJ.200301.0008
- 李耀泰、郭春花、陳天惠、關龍錦、郭宗正、陳福民（2008）。Efficacy of Mifepristone Followed on the Same Day by Misoprostol for Early Abortion。南臺灣醫學雜誌，4(2)，100-103。https://doi.org/10.6726/MJST.200809_4(2).0004
- Ngai, S. W. (2000). Clinical applications of misoprostol in obstetrics and gynecology [master's thesis, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200003478