A Newly Developed Barium Mixture as a Computed Tomography Oral Contrast Agent

自我發展一種新鋇劑混合液作為電腦斷層攝影口服顯影劑的初步使用經驗

陳中和(Jeon-Hor Chen) ； 蘇友吉(Yeo-Gie Su) ； 沈戊忠(Wu-Chung Shen) ； 蔡志文(Jye-Wen Chai) ； 李三剛(San-Kan Lee)

《Mid-Taiwan Journal of Medicine》 3卷4期 (1998/12) Pp. 212-217

https://doi.org/10.6558/MTJM.1998.3(4).4

摘要

本研究主要目的在發展一種安全、便宜且容易泡製的自製鋇劑混合液以作為腹部電腦斷層攝影檢查時的口服顯影劑。此類顯影劑目前在臺灣並無進口。本鋇劑混合液由低量硫化鋇及兩種阻抗性澱粉（resistant starch）Xanthan gum及gelose 50所組成。體外實驗發現其穩定度極佳，在沖泡後72小時仍然均勻懸浮且沒有沉澱產生。體內實驗發現此鋇劑混合液均勻分布在腸胃道各部，其顯影效果極佳，其所接觸之腸胃壁清晰可見，且無明顯假影產生。病人在吞服時至24小時後追蹤並無嘔吐、腹痛及腹瀉等副作用產生。另一優點為此自製鋇劑混合液極為便宜，以平均一次腹部電腦斷層攝影檢查以飲用900毫升鋇劑混合液為例，只需新台幣10圓。

關鍵字

鋇劑混合液 ； 腹部電腦斷層攝影 ； 阻抗性澱粉

並列摘要

The objective of this study was to develop a safe, cheap, and easily prepared dilute barium mixture as an oral contrast agent for abdominal computed tomography examinations which is currently not available in Taiwan at this time. The barium mixture we developed consists of a low concentration of barium sulfate and resistant starches including Xanthan gum and gelose 50. An in vitro study was performed and it showed that the stability of this newly developed formula is excellent. Further in vivo studies revealed that the opacification of this agent in various parts of the bowel loops is adequate and without the formation of sedimentation or perturbing artifacts. No immediate or delayed side effects were found after the ingestion of this barium mixture.

並列關鍵字

barium mixture ； computed tomography ； resistant starch