This article describes a nursing process, through which a home health nurse assisted a caregiver on a SCI case with complicated acute urine retention using urine catheter. By applying the Roy Adapation Model of Nursing as a tool, the patient who found to have health problems, such as excretion function changed, caregiver role strain, fluid volume deficit, and hopelessness. Through the proper deployment of the nursing process, the home health nurse taught the patient and caregiver to face the health problems, improve their knowledge, and improve their self-care abilities. Moreover, by offering the resource of social welfare, the caregiver's stress was released. Therefore, their quality of life were improved.