This study used the "Career Development Patterns Scale" to analyze the career development patterns of the gifted student with autism spectrum disorder (G/ASD) in general high school. This study adopted individual interviews, document analysis and SWOT analysis to understand the decisive factors of career decision-making. The results indicated that the case had multiple strengths, yet the differentiation was not clear. There were five types of the strengths of vocational pattern; the strength of academic pattern was Scientific pattern, consistent with academic tracks; and career decision-making was goal-oriented. This paper is expected to shape a general outline of the career development of G/ASD, and assists twice-exceptional students to develop their careers.