This paper attempted to explore the teaching of concept mapping for the gifted, formulate the teaching model, and analyze the effect after the implementation. In the first step of our analysis, we examined the learning characteristics and thinking process of the gifted students, formation of concept, and students’ learning with concept mapping. Throughout the basic biology course taken by 10th graders examined by experts in actual classroom setting, we then used concept maps as part of instruction to explore the teaching procedure and methods, instructional strategies, media, and assessment techniques. After the use of concept maps in teaching, the gifted students demonstrated improved higher order thinking skills and emotional attitudes. An e-learning platform was also built during the courses, not only allowing the students to evaluate each other’s work and share resources, but also offering the teachers an opportunity to reflect on their teaching and examine their role in instruction. The paper concluded with some implications for education and future researches.