Thrombosis of the venous channels in the brain is an uncommon cause of cerebral infarction relative to arterial disease but is an important consideration because of its potential morbidity. The clinical presentation is highly variable and nonspecific ranging from merely a simple headache to a deadly coma. Women have a higher incidence than men. The use of oral contraceptives and being a sufferer of migraine increase the risk of the development of cerebral venous thrombosis (CVT). Herein, we present a brief review of CVT and report a 17-year-old woman who developed migraine and ischemic stroke due to CVT following oral contraceptives medication. Medical management of patients with CVT is similar to that of patients with arterial stroke as far as stabilizing the patient is concerned.