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【論文摘要】Heart Rate Recovery Improvement in Patients Following Acute Myocardial Infarction

【論文摘要】運動訓練針對急性心肌梗塞患者心率恢復的影響

摘要


Background and Purpose: Heart rate recovery (HRR) is a marker of vagal tone that is a powerful predictor of mortality in patients with coronary artery disease. However, there are limited data discussing the training effect on the HRR in patients with acute myocardial infarction (AMI). The purpose of this study was to evaluate the effect of cardiac rehabilitation (CR) program on heart rate (HR) recovery and maximum oxygen consumption (VO2max) in patients with recent AMI. Methods: Forty patients (38 males, 2 females) who were 6 weeks after an AMI attack were enrolled into our study. Each patient underwent the symptom-limited exercise tests before and after the CR intervention. The cardiorespiratory variables including VO2max, HR recovery at the 1st and 2nd minutes, resting blood pressure (BP), and Max HR were also measured during the exercise testing. All patients completed two 30-minutes aerobic training with physical therapist (PT) supervised and one home-based exercise a week for 12 weeks. A paired t-test was applied to compare the differences of all outcome indicators before and after the intervention. Results: After 12 weeks training, mean VO2max significantly increased by 27% (20.86 to 26.59 liters/min, p < 0.001) and HRR was significantly increased by 32% (11.13 to 14.78 beats/min, p < 0.05) at the 1st minute and 37% (20.14 to 27.69 beats/min, p < 0.001) at the 2nd minutes. In addition, the duration of exercise was also increased (14.50 to 21.20 minutes). Conclusions: It is effective and beneficial in improving VO2 max and HRR significantly in patients with recent AMI under 12 weeks CR intervention. Furthermore, the design of CR program including two 30- minutes aerobic training with PT supervised and home-based exercise once a week was feasible and effective. Clinical Relevance: These findings may provide important information to help the design of intervention program for patients with recent AMI.

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