【論文摘要】Effect of Intravascular Laser Irradiation of Blood on Maximal Oxygen Consumption in Patients With Acute Coronary Syndrome: A Pilot Study

【論文摘要】靜脈雷射在冠心症族群對最大攝氧量的效果：初探研究

黎桂珍(Kuei-Chen Lee) ； 蔣尚霖(Shang-Lin Chiang)

《物理治療》 47卷4期 (2022/12) Pp. 305-305

https://doi.org/10.6215/FJPT.202212.P09

摘要

Background and Purpose: Intravascular laser irradiation of blood (ILIB), which can increase microcirculation and improve oxygen supply, was developed to treat cardiovascular diseases. Peak oxygen consumption (VO_2 max) is important for functional performance in patients with acute coronary syndrome (ACS). The aim of this study was to investigate the effect of ILIB intervention on VO_2 max in patients with ACS. Methods: Two patients with ACS status post percutaneous intervention (PCI) were included. They received a 632.8-nm ILIB (continuous wave laser, 3.0 J/cm^2 progressed to 3.5 J/ cm^2) for 1 hour/day for 10 days. Before and after the ILIB treatment, they performed the symptom-limited exercise test with cycling, and their VO_2 max was measured. Results: The two participants were 36-and 57-year-old male patients who had had an ACS attack and PCI intervention within 3 months before the study. The younger patient showed improvement in VO_2 max after the ILIB treatment from 16.3 ml/ (kg．min) to 17.3 ml/(kg．min), and the other patient, from 18.5 ml/(kg．min) to 19.4 ml/(kg．min). However, the improvements in VO_2 max were not significantly higher than the values before the treatment (p = 0.18). The non-significance of the results may be attributed to the small sample size and short treatment duration. Conclusions: ILIB treatment seems beneficial for the improvement of VO_2 max in the patients with ACS post PCI intervention. The following parameters are recommended: wavelength of 632.8 nm, irradiation dose of 3.0 to 3.5 J/cm^2, and ＞ 10 treatment sessions. Clinical Relevance: According to our results, ILIB could be a supplementary treatment for patients with ACS.