The philosophy of classical physics is "realism". It only attaches importance to the- "matter" but ignores the "mind". On the other hand, the philosophy of quantum mechanics is that there is no objective entity. The philosophy of quantum mechanics clarifies the relationship between the "able-observing mind" and the "observed object". Plenty of scientific evidences show that someone want to perfectly interpret the results of these quantum experiments, the "observers" cannot be excluded. Therefore, "scientific realism" is merely an illusory hypothesis that cannot be verified by quantum experiments. After further discussion, we can be sure that the "Copenhagen interpretation" of quantum mechanics is perfectly consistent with what is the version of "knowing" and "being known" in Buddhism.